LSC-30063 - Brain Disease
Coordinator: Samaneh Maysami Room: HUX-304 Tel: 01782 733671
Lecture Time: See Timetable...
Level: Level 6
Credits: 15
Study Hours: 150
School Office: 01782 734414

Programme/Approved Electives for 2021/22

None

Available as a Free Standing Elective

No

Co-requisites

None

Prerequisites

Neuroanatomy and neurophysiology,

Barred Combinations

None

Description for 2021/22

In this module, you will learn about the pathophysiology, aetiology, and predisposing factors of a number of common neurological, neurodegenerative and neuropsychiatric disorders.
You will study clinical manifestations of neurological disorders, cellular and molecular mechanisms, and advances made in diagnosis, prevention, prediction and treatments of these pathologies.
Problem Based learning (PBL) sessions will enable you to develop transferable skills such as team work, group-based learning, and problem solving.

Aims
The module aims to provide a detailed critical understanding of the theories and techniques underlying modern research into the aetiology, pathology, underlying mechanisms, prevention and treatment of human neurological disorders.

Talis Aspire Reading List
Any reading lists will be provided by the start of the course.
http://lists.lib.keele.ac.uk/modules/lsc-30063/lists

Intended Learning Outcomes

Explain what is a stroke in relation to the brain¿s blood supply, and what are the typical neurological symptoms and underlying cellular and molecular mechanisms: 1,2
Recognise the normal anatomy and operation of the brain¿s ventricular system and how blockages or infections can lead to hydrocephalous or meningitis: 1,2
Explain the pathophysiology (cellular and molecular mechanisms) of neurodegenerative disorders such as Parkinson¿s and Huntington's disease: 1,2
Explain the pathophysiology of multiple sclerosis and known/proposed underlying (cellular and molecular) mechanisms of demyelination/remyelination: 1,2
1,2
Explain the pathophysiology (cellular and molecular mechanisms) and known aetiology of Alzheimer¿s disease: 1,2
Describe partial and generalised seizures and their neurobiological basis: 1,2
Review current understanding of the pathophysiological mechanisms underlying brain cancers (benign and malignant primary tumours): 1,2
Explain pathophysiology of schizophrenia pathology, symptoms and known cellular and molecular mechanisms:

Study hours

8x 1 hour tutorials/workshops
4x 2 hours PBL tutorials (in situ)
10x 5 hours engagement with asynchronous content
40 hours completion of assessment 1
2 hours completion of exam
42 independent study

School Rules

Biology students may not take this module with LSC-30003 Applied Insect Ecology.

Description of Module Assessment

1: Coursework weighted 50%
Problem based learning questionnaire
Students will work in groups of 10 to evaluate a case study. Each learner will independently answer a questionnaire based on the topic they have studied as a group. Each questionnaire will consist of 6-12 short answer questions.

2: Open Book Examination weighted 50%
Online open book examination
The paper will be released on KLE as a Word document at 9am on the morning of the exam. The paper consists 1 essay selected from 3. Students should address each topic using Word, clearly labelling each chosen topic as they provide their answers. Work will be submitted to Turnitin no later than 5pm on the day of release. International students will be asked to notify the School if they need an extension due to different time zones. Although students have been given significant time to complete this exam script, we expect most students to spend no more than 2 hours on completion of this assessment. Answers should be as accurate and concise as possible. Typical answers would be in the range of 500-750 words per topic. We recommend that students do not exceed 750 words per essay-based question as we will be assessing the quality of your answer, not the quantity.