Programme/Approved Electives for 2024/25
None
Available as a Free Standing Elective
No
Cell biology and biochemistry are the foundation of modern medicine and recent advances in these disciplines have provided many tools to dissect the function of a gene and understand how mutations have an impact on biological processes and diseases. This module is designed to give you a firm and detailed overview of the ¿chemistry of life¿ and to understand how this underlies the functioning of the cell at a molecular level. Lectures in the traditional and virtual format will be complemented by a series of practical sessions that will support your understanding of nucleic acids and their manipulation.
Aims
The understanding, diagnosis and treatment of disease is increasingly grounded in the molecular biosciences. This module aims to provide an introduction to biology at the molecular and cellular level, and considers what cells are, what they look like, and how they work. It will establish the principles and knowledge base of biochemistry to give students the means to build understanding of living things at the molecular level; and will convey how molecules, large and small, cooperate so that our cells are able to utilise food as fuel, to produce and respond to messengers that enable communication and coordination between different tissues.
Talis Aspire Reading ListAny reading lists will be provided by the start of the course.http://lists.lib.keele.ac.uk/modules/pha-10030/lists
Intended Learning Outcomes
Describe the structure and function of the key molecules of life ¿ protein and amino acids, simple carbohydrates and lipids, and nucleic acids.: 1,2,4Recognise how the fundamental laws of thermodynamics and kinetics constrain chemical and biological reactions, and the strategies that have evolved to allow biological reactions to work within these constraints.: 1,2,4Explain how lipids and proteins interact to form a functionalised cell membrane, and the role of such membranes in compartmentalising cell activity in organelles; in facilitating cell-cell interactions; and in harnessing the energy of electrochemical gradients to power the cell.: 1,2,4Perform basic analysis of biochemical and cell biology data.: 1,2,3,4
Lectures: 34 hours Workshops: 9 hoursLaboratory sessions: 32 hours Assessed laboratory practicals and exam: 10 hours Independent study: 215 hours
Description of Module Assessment
1: Exam weighted 20%A 2-hour exam at the end of semester one comprising of MCQ and short answer questions
2: Laboratory Practicals weighted 30%Laboratory assessment
3: Assignment weighted 30%In-course assignments
4: Exam weighted 20%A 2-hour exam at the end of semester two comprising of MCQ and short answer questions