Cardiovascular

The Keele Cardiovascular Research Group aims to deliver high-quality, cutting-edge big data cardiology research linking electronic health data from patients with cardiovascular disease to inform the diagnosis, treatment and clinical outcomes of real-world patients with cardiovascular disease. We use national audit data derived from the national cardiovascular societies at the National Institute of Cardiovascular Outcomes Research (NICOR; https://www.ucl.ac.uk/nicor), data derived from primary care (Clinical Practice Research Datalink; https://www.cprd.com/intro.asp) as well as large datasets from the US such as the National Health and Nutrition Examination Survey (NHANES), Nationwide Inpatient Sample, National Readmissions Dataset and CDC (Centre for Disease Control and Intervention) to study outcomes in patients with cardiovascular disease. Our work is cross thematic, with work around interventional cardiology, cardio-oncology, comorbidities, women's cardiovascular health and inequalities and focuses around studying clinical outcomes, complications and assessment of treatment efficacy of interventions / medical treatments using real world data derived from the national electronic healthcare records of patients with cardiovascular disease, as well as prognostic modelling leading development of risk stratification tools used for national reporting.

Professor Mamas co-leads the data science theme of the British Heart Foundation centre of excellence at the University of Manchester and is is part of the NIHR Biomedical Research Centre theme of thrombo-inflammation in collaboration with the University of Birmingham.