Skip to main content Accessibility
Home
Skip to main content Accessibility Home
  • Foundation
  • Undergraduate 2025
  • Postgraduate
  • Research
  • CPD
    •
  • Student Home
  • Welcome new students
  • Cost-of-living support
  • Health and wellbeing
  • Let us know
  • Student KLE
  • Staff Directory
  • Library
    •
  • Intranet
    •
    Alumni
  • Faculties
  • Schools
  • Institutes
  • Research Institutes
    •
  • China
  • Hong Kong SAR
  • India
  • Kenya
  • Nigeria
  • Pakistan
  • Saudi Arabia
  • UK International
  • Rest of the world
  • Visa
    •
    Dr Monte Gates

    Dr Monte Gates

    Title
    Senior Lecturer in Medicine & Neuroscience
    Location
    Huxley Building : 204a
    Role
    ISTM Research theme: Therapeutics
    Contact me
    Try my office or arrange an appointment by e-mail.
    Phone
    +44 (0)1782 733875
    Email
    m.a.gates@keele.ac.uk

    Biography

    ROSA TH Z-Series 20x I graduated with a BS in Experimental Psychology, and a BA in Philosophy from Austin Peay State University in the US.  From there, I went on to do my PhD in Anatomy and Neurobiology at the University of Tennessee (UT), where I researched how astrocytes (glial cells) affect the development and repair of neural circuits in the central nervous system. 

    After successfully completing my degree at UT, I was fortunate to work 2.5 years in the laboratory of Dr. Anders Bjorklund (the innovator of the technique of neural transplantation for Parkinson’s disease) at Lund University in Sweden, where I conducted studies on the possibility of astrocyte phenotypes existing in the brain.  Following my studies there, I went to Harvard University where I became a postdoctoral Fellow, working with Dr. Jeffrey Macklis to study development of cortical projection neurons and axon guidance. 

    After 3 years at Harvard University, I begin working with Professor Stephen B. Dunnett at Cardiff University, where I conducted work on the emergence and development of dopaminergic neurons in the developing brain.  I then came to Keele University where I have (hopefully) combined this body of work by beginning studies on  what proteins and cells are involved in the development of motor circuitry in the central nervous system.  

    Research and scholarship

    ISTM Research theme: Therapeutics

    Cerebellum 20x combined adjusted brightened

    My lab focuses on the use of proteomics, cell culture, and in vivo models to understand how cells develop and find appropriate targets in the central nervous system.   Over the past 5 years, we have developed a unique device to transplant tissue and constructs into the brain for repair, and have begun to describe changes (at the molecular level) in the brain as it develops, ages, and degenerates.  

    We have a great deal of interest in Parkinson’s disease, and how dopamine neurons are born, develop and degenerate.  We are particularly interested in how dopamine neurons, and other neurons involved in the motor output of the brain (e.g., cortico-spinal neurons) find their appropriate target / connection during development.  The hope of this research is to find ways to (re) wire the brain to repair diseases and disabilities that affect an individual’s ability to move.

    Publications

    School of Life Sciences,
    Huxley Building,
    Keele University,
    Staffordshire,
    ST5 5BG
    Tel: +44 (0) 1782 734414