Inflammation; Infection; Immunology

PhD / MPhil

Duration: PhD – 3 years full-time, 6 years part-time
MPhil – 1 year full-time, 2 years part-time

Contact: Dr Marcelo Lima; m.andrade.de.lima@keele.ac.uk; (+44) 01782 734111

How to apply
Apply for PhD
Apply for Distance PhD
Apply for MPhil
Apply for Distance MPhil
Fees and finance
Entry requirements

Summary

This research area includes both basic and clinical research, including topics such as rheumatology, the structural immunology of innate immune proteins, fish immunology and apoptosis.

Overview Research interests

Overview

This research area includes both basic and clinical research, including topics such as rheumatology, the structural immunology of innate immune proteins, fish immunology and apoptosis.

The main objective of the research at the Staffordshire Rheumatology Centre (SRC) at the Haywood Hospital is to enable a better understanding of disease mechanisms involved in the development and progression of rheumatic diseases, and to identify factors predictive of disease outcome. This includes investigation of comorbid diseases (e.g. cardiovascular disease) and mortality as well as disease specific outcomes.

Rheumatology research at the RJAH, Oswestry is focused on the mechanism of leukocyte migration into sites of inflammation. On Keele campus the Structural biology research group is studying the interaction between pathogens such as Haemophilus influenzae and influenza virus and lung surfactant protein D, as well as the structure, function and evolution of the serum pentraxins CRP and SAP. Apoptosis research includes the control of apoptosis (programmed cell death) in human cells, and on the ways in which this programme goes wrong to produce disease.

Research interests

Research Subject Areas:

Rheumatology - Dr Derek Mattey
Structural immunology - Professor Trevor Greenhough; Dr Annette Shrive
Comparative Immunology - Professor Dave Hoole
Apoptosis- Dr Sheila Hope; Professor Dave Hoole; Professor Gwyn Williams
Immunomodulation - Professor Nick Forsyth
Antimicrobials - Dr Wen-Wu Li

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